Cyproterone Acetate Powder Quick Details:
Cyproterone Acetate Powder
CAS No.: 427-51-0
Storage temp.: 2-8°C
Purity: 99% min
Appearance: White Crystalline Solid
Usage: The free alcohol is an anti-androgen; the acetate is both an anti-androgen and a progestogen. Combined with estrogen it is used in the treatment of acne.
Cyproterone Acetate Powder Description:
Cyproterone acetate, sometimes abbreviated as CPA, and sold under brand names such as Androcur and Cyprostat, is a synthetic steroidal antiandrogen drug with additional progestogen and antigonadotropic properties.Its primary action is to suppress the activity of the androgen hormones such as testosterone and its more potent metabolite dihydrotestosterone (DHT) in the body, effects which it mediates via competitive antagonism of the androgen receptor and inhibition of enzymes in the androgen biosynthesis pathway.
Cyproterone Acetate Powder Function:
Reduce male paraphilic sexual desire; not operation of prostate cancer; severe masculinization of female signs: like the very severe hirsutism, androgen-dependent severe hair loss, ultimately leading to the bald ( severe androgenetic alopecia ), often accompanied by severe acne and / or seborrheic.
Cyproterone Acetate Powder Application:
Cyproterone acetate has antagonistic properties towards the androgen receptor with an IC50 value of 7.1 nM. It can however, also act as a partial agonist of AR at an EC50 of 4.0 μM. In the presence of 10 nM testos terone, low concentrations of Cyproterone acetate inhibits T-stimulated transcription of 3XHRE-LUC, but at higher concentrations, transcription is stimulated.Cyproterone Acetate is also a hepatomitogen and tumor promoter and induces apoptosis in hepatocytes.
Cyproterone Acetate Powder Certificate of Analysis: